- Salvation Army, Gananoque
- Sand Gravel & Aggregate, Gananoque
- Sandwich Shop Restaurants, Gananoque
- Satellite & Cable TV Equipment & Systems Repair & Service, Gananoque
- Seafood Restaurants, Gananoque
- Secondary Schools, Gananoque
- Secretarial & Court Reporting Services, Gananoque
- Septic Systems Installation & Repair, Gananoque
- Septic Tank Pumping & Cleaning, Gananoque - Septic Systems
- Septic Tanks & Septic Systems Contractors, Gananoque - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Ship & Boat Building & Repairing, Gananoque
- Shoe Stores, Gananoque - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Gananoque
- Sightseeing Tours, Gananoque
- Signs, Gananoque
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- Snacks & Desserts, Gananoque
- Social Services & Welfare, Gananoque
- Societies & Foundation Associations, Gananoque
- Special Needs Transportation, Gananoque
- Specialty Animal Services, Gananoque
- Specialty Stores, Gananoque
- Specialty Vehicle Rental & Leasing, Gananoque
- Sporting Goods Stores, Gananoque
- Sports & Recreational Services, Gananoque
- Staffing & Support Services, Gananoque
- Stationery & Office Supplies, Gananoque
- Stoves & Furnace Equipment, Gananoque - Fittings & Repair Parts
- Stress Management & Counseling, Gananoque
- Submarine Sandwich Restaurants, Gananoque
- Substance Abuse Outpatient Clinics, Gananoque
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