- Salvation Army, Tweed
- Sand Gravel & Aggregate, Tweed
- Sandwich Shop Restaurants, Tweed
- Seafood Restaurants, Tweed
- Secondary Schools, Tweed
- Security Brokers & Dealers, Tweed
- Senior Citizens Housing, Tweed
- Septic Systems Installation & Repair, Tweed
- Septic Tanks & Septic Systems Contractors, Tweed - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Shopping & Shopping Services, Tweed
- Signs, Tweed
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- Snowmobile Dealers, Tweed - Parts, Gear, Clothing & Accessories
- Social Services & Welfare, Tweed
- Special Events Photographers, Tweed
- Specialty Animal Services, Tweed
- Specialty Stores, Tweed
- Sporting Goods Stores, Tweed
- Stadiums, Arenas, Coliseums & Athletic Fields, Tweed
- Steel Work Contractors, Tweed
- Stone & Rock Quarry, Tweed - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Stoves & Furnace Equipment, Tweed - Fittings & Repair Parts
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