- Salvation Army, Wiarton
- Sand Gravel & Aggregate, Wiarton
- Sandwich Shop Restaurants, Wiarton
- Sawmill & Planing Mills, Wiarton
- Sawmill Supplies & Equipment Repair, Wiarton
- Scientific & Laboratory Equipment & Instruments, Wiarton
- Seafood Restaurants, Wiarton
- Secondary Schools, Wiarton
- Senior Citizens Housing, Wiarton
- Septic Systems Installation & Repair, Wiarton
- Septic Tanks & Septic Systems Contractors, Wiarton - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewing & Yarn Stores & Supplies, Wiarton
- Sheet Metal Contractors, Wiarton - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Wiarton
- Shoe Repair Shops, Wiarton
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- Shoe Stores, Wiarton - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Wiarton
- Siding Contractors, Wiarton - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Social Clubs & Organizations, Wiarton
- Social Services & Welfare, Wiarton
- Societies & Foundation Associations, Wiarton
- Special Interest Schools Or Instruction, Wiarton
- Speciality Food Stores, Wiarton
- Specialty Stores, Wiarton
- Sporting Goods Stores, Wiarton
- Staffing & Support Services, Wiarton
- Stone & Rock Quarry, Wiarton - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Stone Setting Contractors, Wiarton
- Storm Doors & Windows, Wiarton
- Surveyor Services, Wiarton - Surveying Service
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